My research is embedded within the Donders Institute for Brain, Cognition and Behaviour of Radboud University Nijmegen. I am Principal Investigator in two of its research centres, the Centre for Cognition and the Centre for Neuroscience and affiliated PI at the Nijmegen Centre for Evidene-Based Practice (NCEBP) at the Radboud University Medical Center in Nijmegen. Below are my main research topics.
Working memory in relation to episodic memory formation
This research investigates the neural basis of working-memory binding and episodic memory formation focusing on neuroimaging techniques (fMRI and fNIRS) and neuropsychological patient studies. This research is supported by an NWO VIDI grant. We also investigate working-memory function in relation to age-related compensation using funtional near-infrared spectroscopy (fNIRS, collaboration with Dr. Jurgen Claassen, MD). Here I collaborate with the Centre for Cognitive Neuroimaging, Alzheimer Centre Nijmegen and Vincent van Gogh Institute for Psychiatry in Venray.
Cognitive determinants of dementia and MCI
Studies on the underlying cognitive processes of dementia and MCI, relation between cognition, moderator variables and outcome measures, in collaboration with Prof. Dr. Marcel Olde Rikkert, MD.
Human memory (general)
Studies focusing on memory deficits after brain damage, spatial memory, confabulation and memory function in healthy individuals, in collaboration with Dr. Paul Eling, Dr.Joukje Oosterman and Dr. Marc Hendriks.
Studies focusing on the role of implicit and explicit memory in compensatory mechanisms in brain-injured patients (e.g., errorless learning), in collaboration with Prof. Dr. Luciano Fasotti and the effects of group psychotherapy in patients with mild cognitive impairment (collaboration with Liesbeth Joosten, MSc).
Vascular cognitive impairment
PhD-projects on vascular cognitive impairment (VCI) and vascular dementia inpatients with the metabolic syndrome or diabetes mellitus type 2 in close collaboration with Dr. Geert-Jan Biessels, MD of the Department of Neurology of Universty Medical Center Utrecht. This research is supported by a High Potential grant from Utrecht University. I also collaborate with Dr. Frank-Erik de Leeuw on vascular cognitive impairment and young stroke.
Development and validation of new neuropsychological and experimental test procedures, mainly in the domain of human memory and learning (e.g. the Dutch translation and validation of the Rivermead Behavioural Memory Test - Third Edition and the Wechsler Memory Scale-IV). Here, I collaborate with Dr. Marc Hendriks and Pearson Test Publishers.